US Dilated Cardiomyopathy Therapeutics Market Analysis

US Dilated Cardiomyopathy Therapeutics Market Analysis


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US Dilated Cardiomyopathy Therapeutics Market is projected to grow from $xx Mn in 2023 to $xx Mn by 2030, registering a CAGR of xx% during the forecast period of 2023 ? 2030. The phrase "dilated cardiomyopathy" refers to conditions that affect the heart muscle and is regarded as a deadly cardiac condition. Reduced myocardial contractility and left and right ventricular dilatation are usually its defining characteristics. The potential driving force behind the DCM Therapeutics Market has been the rise in diagnostic alterations and symptom awareness, as well as declining dietary and lifestyle choices that have led to an increase in the occurrence of disease. The government is sponsoring research and development (R&D) projects to encourage scientists and pharmaceutical firms to create novel treatments. Array BioPharma, Inc., AstraZeneca plc, Celladon Corporation, GlaxoSmithKline plc, Janssen Pharmaceuticals, Inc. (J&J), Merck & Co., Inc., Novartis International AG, Pfizer, Inc., Sanofi S.A., Teva Pharmaceutical Industries Ltd., Vericel Corporation, and many others are key players in the market for cystic fibrosis (CF) therapeutics.

ID: IN10USRD020 CATEGORY: Rare Diseases GEOGRAPHY: US AUTHOR: Nipun Arora

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US Dilated Cardiomyopathy Therapeutics Market Analysis Summary

US Dilated Cardiomyopathy Therapeutics Market is valued at around $12.18 Mn in 2022 and is projected to reach $12.88 Mn by 2030, exhibiting a CAGR of 0.7% during the forecast period 2023-2030.

The term "dilated cardiomyopathy" (DCM) describes the myocardium's weakness, consequent dilatation, and malfunction. Concomitant hypertrophy is typically present as well. The heart is typically enlarged and flabby in DCM. In DCM, there are no distinct histologic abnormalities. DCM has a variety of causes, including genetic factors (30 to 50% of cases), toxic factors (such as alcohol and chemotherapy drug doxorubicin), metabolic factors (such as iron overload in hereditary hemochromatosis), viral factors, and antecedent myocardial infarction. Nearly 20% of instances of DCM are caused by mutations in the TTN gene, which codes for the Titin protein. Dilated cardiomyopathy is frequently brought on by the Trypanosome cruzi-caused Chagas disease in Latin America.

The potential driving force behind the DCM Therapeutics Market has been the rise in diagnostic alterations and symptom awareness, as well as declining dietary and lifestyle choices that have led to an increase in the occurrence of disease. The government is sponsoring research and development (R&D) activities in an effort to encourage scientists and pharmaceutical businesses to create novel medications.

Array BioPharma, Inc., AstraZeneca plc, Celladon Corporation, GlaxoSmithKline plc, Janssen Pharmaceuticals, Inc. (J&J), Merck & Co., Inc., Novartis International AG, Pfizer, Inc., Sanofi S.A., Teva Pharmaceutical Industries Ltd., Vericel Corporation, and many others are key players in the market for cystic fibrosis (CF) therapeutics.

Market dynamics

Market Drivers

Different diagnostic tests used to treat peripartum cardiomyopathy are increasing, which is helping the market's growth. To find the presence of particular abnormalities, various techniques are used, such as cardiac MRI and electrocardiography. As a result, it plays a key role in the market's expansion.

Increasing The market for DCM therapies is also being driven by the prevalence of DCM.

Changes in Lifestyle: Smoking is one of the top causes of preventable illness and death in the United States. Every year, it causes more than 480,000 deaths. Additionally, the modern population's adopted lifestyles that include an unhealthy way of living, a poor diet, stress, and many other similar problems all contribute to the market's expanding prospects.

An increase in research and development (R&D) activities: R&D activities are one factor boosting the market's growth. As a result, the market for dilated cardiomyopathy will benefit globally. The government is sponsoring research and development (R&D) projects to encourage scientists and pharmaceutical firms to create novel treatments. For instance, TN-301 (TYA-11631) is being developed to treat hereditary dilated cardiomyopathy and heart failure (HF) with preserved ejection fraction (HFpEF) (DCM). Oral administration is the method used. The potential medication works by inhibiting histone deacetylase 6. (HDAC6).

 

Development in Dilated Cardiomyopathy Therapeutics Market

For the treatment of hereditary dilated cardiomyopathy and heart failure (HF) with preserved ejection fraction (HFpEF), TN-301 (TYA-11631) is being developed (gDCM). Oral administration is the method used. The potential medication works by inhibiting histone deacetylase 6. (HDAC6).

In order to meet important clinical requirements for people with hereditary heart disease, MyoKardia is creating a pipeline of innovative small-molecule medicines. One million persons in the United States suffer from hypertrophic and dilated cardiomyopathy combined, and for which no innovative treatments have been made available in the market in more than ten years.

Preclinical AAV-based gene therapy programmes are being developed by Rocket Pharmaceuticals for the treatment of PKP2-arrhythmogenic cardiomyopathy (ACM) and BAG3-associated dilated cardiomyopathy (DCM).

Key players

Abbott Laboratories Amgen AstraZeneca Bristol-Myers Squibb Eli Lilly and Company Janssen Pharmaceuticals Merck & Co., Inc. Novartis AG Pfizer Inc. Roche Holding AG

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Market segmentations for US Dilated Cardiomyopathy Therapeutics Market

By Drug class

  • Angiotensin-converting enzyme (ACE) Inhibitors
  • Beta-blockers
  • Aldosterone antagonists,
  • Angiotensin II Receptor Blockers
  • Others

By Devices

  • Implantable Devices
  • Heart Pumps
  • Cardioverter-Defibrillators
  • Others

By Route of Administration

  • Oral
  • Parenteral
  • Others

By End-User

  • Hospitals
  • Research Institutes
  • Specialty Clinics

By Distribution Channel

  • Hospital Pharmacy
  • Retail Pharmacy
  • Online Pharmacies
  • Others

Insights10 will provide you with the reports within 10 key parameters which are:

  1. Market Overview
  2. Market Growth Drivers & Restraints
  3. Epidemiology of Disease Type
  4. Market Segmentation
  5. Market Share
  6. Competitive Landscape
  7. Key Company Profiles
  8. Healthcare Policies & Regulatory Framework
  9. Reimbursement Scenario
  10. Factors Driving Future Growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision-making for business stakeholders. Our focused approach to developing reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

 

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers, and researchers across countries through which we engage with local experts to gather key data points and assumptions about each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

Secondary Data Collection: We have developed strong expertise and experience in secondary data collection methods for developing unique data sets and research material. We gather data from multiple reliable sources to maintain a high level of accuracy and consistency. The market data is analyzed and forecasted using appropriate statistical and coherent models. The report offers an overall analysis of the market size, growth, and market share as well as a segment-level analysis of the specific market. Our report includes precise, to-the-point information related to the overall market, competition, growth drivers, challenges, regulatory updates, and competition.

Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

 

 

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameters and micro indicators. The macro parameters include changes in government policies, demand and supply of the market, government intervention programs, and major market share. The micro indicators are GDP growth, market size, market volume, etc. We also understand nuances specific to each country like the US, Canada, India, Germany, etc., and have worked across 60+ countries and hence not only understand global trends but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. starting with the large overall market and segmenting different areas and the bottom-up approach i.e. starting with population and epidemiology and rolling up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach is mainly used for new product forecasting and the bottom-up approach is used for demand estimation of any product for different countries summed up to form the total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as Asia-Pacific, Africa, Europe, Middle East, North America, and  Latin America for the period of 2022 to 2030. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape, and policy and regulatory scenario, and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases, and company-level averages, etc.

We make sure to finalize the numbers in alignment with the market research. Firstly, our internal experts ensure thorough validation and checking to ensure accurate and precise analysis and then validation is also done using a multiple-data analysis model. Two-level validation is done and entails the finalization of the report scope and the way of representation pattern.

 

 

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analyzed and synthesized. The second series of interviews are done if necessary to check and validate. The future opportunities are analyzed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results is then, interpreted by considering the following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing the regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue/volume
  • ​Analyzing current needs and determining penetration to estimate the market

Insights: Our reports deliver actionable insights backed with supporting facts and figures to assist you in achieving exemplary growth. Our in-depth analyses are interspersed with relevant insights and statistics to offer an executive-level view of a given market. The description helps in correlating many minor factors affecting the market and their impact on the different segments within the market.

Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

Presentation & Reporting: The market research report is presented in different forms such as charts by using a scientific approach for easy understanding. Historic, current, and future analysis is provided for each market in terms of both value and volume. The size of the market is interpreted in the US Dollar value and the respective unit, based on the product, for volume consumption.

The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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This report addresses

  • Intelligent insights to take informed business decisions
  • Qualitative, acute and result oriented market analysis
  • Market size and forecasts from 2022 to 2030
  • Opportunities for expansion and in-depth market analysis
  • Segmentation and regional revenue forecasts
  • Analysis of the market share and competitive landscape
  • Strategic Recommendations to chart future course of action
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Last updated on: 04 July 2023
Updated by: Ritu Baliya

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