US Cryptococcosis Therapeutics Market Analysis

US Cryptococcosis Therapeutics Market Analysis


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US Cryptococcosis Therapeutics market is projected to grow from $xx Mn in 2023 to $xx Mn by 2030, registering a CAGR of xx% during the forecast period of 2023 ? 2030. The pathogenic yeasts in the genus Cryptococcus that cause cryptococcosis have a wide range of clinical manifestations and are contagious throughout the world. Currently, Cryptococcus neoformans and Cryptococcus gattii are the two species of the bacteria most frequently linked to human illness. The market for disorders caused by cryptococcosis is expanding as a result of the rising prevalence of the condition and the availability of cutting-edge treatments. Bristol-Myers Squibb, Abbott Laboratories, Pfizer, Glenmark Pharmaceuticals, Bausch Health, Johnson & Johnson, Novartis AG, Janssen Biotech, Sigmapharm Laboratories, Matinas BioPharma, Mycovia Pharmaceuticals, Aparna Biosciences, FUJIFILM Toyama Chemical, TGV Therapeutics, Amplyx Pharmaceuticals, and many others are leading companies in the global market for Cryptococcosis therapeutics.

ID: IN10USRD017 CATEGORY: Rare Diseases GEOGRAPHY: US AUTHOR: Nipun Arora

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US Cryptococcosis Therapeutics Market Analysis Summary

US Cryptococcosis Therapeutics Market is valued at around $2.33 Bn in 2022 and is projected to reach $3.47 Bn by 2030, exhibiting a CAGR of 5.1% during the forecast period 2023-2030.

The pathogenic yeasts in the genus Cryptococcus that cause cryptococcosis have a wide range of clinical manifestations and are contagious throughout the world. Currently, Cryptococcus neoformans and Cryptococcus gattii are the two species of bacteria most frequently linked to human illness. Inhaling dust that contains yeast cells can cause cryptococcosis, which typically affects the lungs. Fever, malaise, cough, hemoptysis (bloody or blood-tinged sputum), headache, and vision abnormalities (blurry or double vision, photophobia) are only a few of the symptoms of cryptococcosis. By employing Indian ink and direct microscopic examination, it is possible to detect yeasts encapsulated in cerebrospinal fluid (CSF) and make the diagnosis of cryptococcosis in 95% of cases. Urine collection, a chest x-ray, and a lumbar puncture come first.

C. neoformans have a distinct culture. Blood cultures may be positive, especially in people with AIDS, but CSF, sputum, and urine are the most often produced bodily fluids. In cases of cryptococcal meningitis, elevated CSF protein and a pleocytosis of mononuclear cells are common. Low glucose levels are common. In CSF or blood samples, or both, the latex test for cryptococcal capsular antigen is positive.

The market for disorders caused by cryptococcosis is expanding as a result of the rising prevalence of the condition and the availability of cutting-edge treatments. Bristol-Myers Squibb, Abbott Laboratories, Pfizer, Glenmark Pharmaceuticals, Bausch Health, Johnson & Johnson, Novartis AG, Janssen Biotech, Sigmapharm Laboratories, Matinas BioPharma, Mycovia Pharmaceuticals, Aparna Biosciences, FUJIFILM Toyama Chemical, TGV Therapeutics, Amplyx Pharmaceuticals, and many others are leading companies in the global market for Cryptococcosis therapeutics.

Market dynamics

Market Drivers

HIV cases: According to the Centers for Disease Control and Prevention and the World Health Organization, 220,000 cases of cryptococcal meningitis are thought to occur worldwide each year among people with HIV/AIDS, leading to close to 181,000 fatalities.

Technology development: The main reasons driving the growth of the market for cryptococcosis disorders are the rising prevalence of the disease and the availability of cutting-edge treatments.

 

Developments in the Cryptococcosis Therapeutics market

Matinas BioPharma, MAT 2203 Amphotericin B, a broad-spectrum fungicidal drug, is formulated as MAT2203, an oral medication that uses Matinas' own lipid nano-crystal ("LNC") delivery technology platform. By encapsulating tiny molecules, nucleic acid polymers like oligonucleotides, vaccines, peptides, proteins, and other medications, the company's LNC delivery technology may make them safer, more acceptable, less toxic, and orally bioavailable.

 

Restraints in US Cryptococcosis Therapeutics market

When patents expire, generic companies are invited to enter the market, which serves to constrain the Cryptococcosis Therapeutics Market.

Key players

AbbVie Astellas Pharma Inc. Gilead Sciences Janssen Pharmaceuticals Merck & Co., Inc. Novartis AG Pfizer Inc. Roche Holding AG Sanofi Theratechnologies, Inc.

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Market segmentations for US Cryptococcosis Therapeutics market

By Treatment

  • Polyenes- amphotericin B and nystatin
  • Triazoles- voriconazole and itraconazole
  • Nucleoside drugs- 5-fluorocytosine

By End User

  • Hospital Pharmacies
  • Retail Pharmacies
  • Drug Store
  • Other

By route of administration

  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical

By molecule type

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy

Insights10 will provide you with the reports within 10 key parameters which are:

  1. Market Overview
  2. Market Growth Drivers & Restraints
  3. Epidemiology of Disease Type
  4. Market Segmentation
  5. Market Share
  6. Competitive Landscape
  7. Key Company Profiles
  8. Healthcare Policies & Regulatory Framework
  9. Reimbursement Scenario
  10. Factors Driving Future Growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision-making for business stakeholders. Our focused approach to developing reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

 

Stage I: Market Data Collection

Primary Interviews: We have developed a network of experts, freelancers, and researchers across countries through which we engage with local experts to gather key data points and assumptions about each market. We also engage regularly with some of the best market research agencies such as Atheneum, GuidePoint, GLG, etc. to conduct surveys and interviews, and build intelligence. We have language translators as a part of our team, who between them can cover 30+ languages allowing us to extract better local insights.

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Data Sources: We have access to multiple highly reliable free and subscription data sources. We have many years of experience to understand which sources are more dependable for what and which to prefer for the reliable and latest information. The key sources of information include the following, but are not limited to:

 

 

Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameters and micro indicators. The macro parameters include changes in government policies, demand and supply of the market, government intervention programs, and major market share. The micro indicators are GDP growth, market size, market volume, etc. We also understand nuances specific to each country like the US, Canada, India, Germany, etc., and have worked across 60+ countries and hence not only understand global trends but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. starting with the large overall market and segmenting different areas and the bottom-up approach i.e. starting with population and epidemiology and rolling up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach is mainly used for new product forecasting and the bottom-up approach is used for demand estimation of any product for different countries summed up to form the total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as Asia-Pacific, Africa, Europe, Middle East, North America, and  Latin America for the period of 2022 to 2030. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape, and policy and regulatory scenario, and the quantitative analysis covers different market estimates and forecasts.

Data Triangulation & Validation:

Data triangulation of various sources and results of the research are carried out by benchmarking with reliable sources such as industry statistics, statistical databases, and company-level averages, etc.

We make sure to finalize the numbers in alignment with the market research. Firstly, our internal experts ensure thorough validation and checking to ensure accurate and precise analysis and then validation is also done using a multiple-data analysis model. Two-level validation is done and entails the finalization of the report scope and the way of representation pattern.

 

 

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analyzed and synthesized. The second series of interviews are done if necessary to check and validate. The future opportunities are analyzed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results is then, interpreted by considering the following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing the regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue/volume
  • ​Analyzing current needs and determining penetration to estimate the market

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Data curated from the analysis and interpretation are drawn to portray all in one consolidated report.

Presentation & Reporting: The market research report is presented in different forms such as charts by using a scientific approach for easy understanding. Historic, current, and future analysis is provided for each market in terms of both value and volume. The size of the market is interpreted in the US Dollar value and the respective unit, based on the product, for volume consumption.

The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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Last updated on: 04 July 2023
Updated by: Ritu Baliya

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