South Africa Constipation Therapeutics Market Analysis

South Africa Constipation Therapeutics Market Analysis


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South Africa Constipation Therapeutics Market was valued at $118 Mn in 2022 and is estimated to reach $215 Mn in 2030, exhibiting a CAGR of 7.73% during the forecast period. The constipation therapeutics market is experiencing worldwide expansion due to factors like aging, sedentary lifestyles, and poor dietary habits. The growing elderly demographic, prone to chronic conditions, plays a significant role in driving this growth. Key players in this industry include AstraZeneca, Bayer AG, Sanofi, Sucampo Pharmaceuticals, Takeda Pharmaceutical, Synergy Pharmaceuticals, Ironwood Pharmaceuticals, Salix Pharmaceuticals, Abbott Laboratories and Cosmo Pharmaceuticals NV.

CATEGORY: Pharmaceuticals GEOGRAPHY: South Africa AUTHOR: Medha Sansanwal

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South Africa Constipation Therapeutics Market Executive Summary

South Africa's Constipation Therapeutics Market was valued at $118 Mn in 2022 and is estimated to reach $215 Mn in 2030, exhibiting a CAGR of 7.73% during the forecast period.

Constipation is a digestive disorder characterized by infrequent, challenging, or hardened bowel movements resulting from the slowed movement of stool through the colon, leading to increased water absorption and solidification of stool. This condition arises from a reduction in the speed at which faeces traverse the large intestine. Common symptoms of constipation include exertion during bowel movements, a feeling of incomplete evacuation, abdominal discomfort, and irregular or infrequent bowel patterns. Various factors, including a low-fiber diet, insufficient fluid intake, lack of physical activity, specific medications, and underlying medical conditions, can contribute to the development of constipation. Managing constipation typically involves making lifestyle adjustments, modifying dietary habits, increasing physical activity, and, when necessary, using medications to address and alleviate symptoms.

In South Africa, constipation is a common issue that impacts people of all ages, with a 20% reported prevalence. Dietary practices are one of the main causes, especially when it comes to diets low in fruits, vegetables, whole grains, and/or low in fiber. The prevalence of constipation is also greatly increased by sedentary lifestyles and a lack of physical activity. The incidence of this condition is further increased by South Africa's aging population, which is predisposed to chronic conditions. The diagnosis and treatment of constipation are complicated in certain areas by limited access to healthcare services. Raising awareness of the value of a balanced diet, increasing physical activity, and guaranteeing access to healthcare services for precise diagnosis and treatment are all part of the effort to combat constipation in South Africa. Public health initiatives and educational campaigns play a vital role in alleviating the impact of constipation in the South African population.

The FDA has granted approval for prucalopride, identified as a selective serotonin-4 (5HT4) receptor agonist, as an oral treatment designed for daily use among adults grappling with chronic idiopathic constipation. Through clinical trials, prucalopride demonstrated noteworthy enhancement in bowel motility, revealing a substantial response rate ranging from 19% to 38% among patients, as opposed to 10% to 20% observed in those receiving a placebo.

South Africa Constipation Therapeutics Market Report 2022 to 2030

Market Dynamics

Market Growth Drivers

Poor Dietary Habits and Sedentary Lifestyles: Constipation is a prevalent issue in South Africa, largely attributed to the widespread adoption of unhealthy eating habits and sedentary lifestyles. The demand for therapeutic solutions to tackle digestive health problems is, in part, connected to shifts in dietary practices, marked by a lack of foods rich in fibre.

Rising Prevalence of Constipation: Approximately 20% of the South African population encounters constipation. As South Africa's population ages, a larger segment becomes prone to constipation due to physiological changes associated with aging. The rising awareness among the public regarding digestive health concerns, including constipation, may result in an increased demand for available treatment options.

Technological Advancements in Treatment Options: Progress in pharmaceutical research and development, resulting in the emergence of enhanced and precisely targeted constipation therapeutics, has the potential to drive market expansion. Novel treatment alternatives demonstrating heightened effectiveness and diminished side effects could attract interest from both healthcare providers and patients.

Market Restraints

Cultural and Dietary Practices: Traditional cultural and dietary practices in South Africa, which may not prioritize a high-fiber diet or active lifestyle, could pose challenges for preventive measures against constipation. Cultural preferences and habits may need to be considered in the development and promotion of therapeutics.

Economic Constraints: Economic considerations, such as diminished income levels in specific population segments, might constrain the accessibility of constipation therapeutics. This limitation could result in a lower uptake of medications or treatments, particularly among individuals facing financial constraints.

Limited Healthcare Awareness: A hindrance to market growth may arise from a lack of awareness or comprehension regarding the significance of gastrointestinal health and the existing therapeutics for constipation. Insufficient awareness among healthcare professionals and the general population could lead to delays or inadequate efforts in seeking treatment.

Healthcare Policies and Regulatory Landscape

In South Africa, the oversight of healthcare policies and regulations related to therapeutic drugs is managed by the South African Health Products Regulatory Authority (SAHPRA). SAHPRA is responsible for activities such as the registration, licensing, and post-market surveillance of various health products, with a specific focus on pharmaceuticals. The Department of Health (DoH) plays a pivotal role in shaping healthcare policies within the country, and adherence to Good Manufacturing Practice (GMP) standards is essential for pharmaceutical manufacturers to ensure the quality and safety of therapeutic drugs. SAHPRA establishes regulations governing clinical trials, and the ongoing implementation of the National Health Insurance (NHI) in South Africa has the potential to influence financing and reimbursement policies for specific drugs.

Competitive Landscape

Key Players

  • AstraZeneca
  • Bayer AG
  • Sanofi
  • Sucampo Pharmaceuticals
  • Takeda Pharmaceutical
  • Synergy Pharmaceuticals
  • Ironwood Pharmaceuticals
  • Salix Pharmaceuticals
  • Abbott Laboratories
  • Cosmo Pharmaceuticals NV

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

South Africa Constipation Therapeutics Market Segmentation

By Therapeutic

  • Laxatives
  • Chloride Channel Activators
  • Peripherally Acting Mu-Opioid Receptor Antagonists
  • GC-C Agonists
  • 5-HT4 Receptor Agonists

By Disease

  • Chronic Idiopathic Constipation
  • Irritable Bowel Syndrome with Constipation
  • Opioid-Induced Constipation

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies
  • Online Pharmacies

Methodology for Database Creation

Our database offers a comprehensive list of healthcare centers, meticulously curated to provide detailed information on a wide range of specialties and services. It includes top-tier hospitals, clinics, and diagnostic facilities across 30 countries and 24 specialties, ensuring users can find the healthcare services they need.​

Additionally, we provide a comprehensive list of Key Opinion Leaders (KOLs) based on your requirements. Our curated list captures various crucial aspects of the KOLs, offering more than just general information. Whether you're looking to boost brand awareness, drive engagement, or launch a new product, our extensive list of KOLs ensures you have the right experts by your side. Covering 30 countries and 36 specialties, our database guarantees access to the best KOLs in the healthcare industry, supporting strategic decisions and enhancing your initiatives.

How Do We Get It?

Our database is created and maintained through a combination of secondary and primary research methodologies.

1. Secondary Research

With many years of experience in the healthcare field, we have our own rich proprietary data from various past projects. This historical data serves as the foundation for our database. Our continuous process of gathering data involves:

  • Analyzing historical proprietary data collected from multiple projects.
  • Regularly updating our existing data sets with new findings and trends.
  • Ensuring data consistency and accuracy through rigorous validation processes.

With extensive experience in the field, we have developed a proprietary GenAI-based technology that is uniquely tailored to our organization. This advanced technology enables us to scan a wide array of relevant information sources across the internet. Our data-gathering process includes:

  • Searching through academic conferences, published research, citations, and social media platforms
  • Collecting and compiling diverse data to build a comprehensive and detailed database
  • Continuously updating our database with new information to ensure its relevance and accuracy

2. Primary Research

To complement and validate our secondary data, we engage in primary research through local tie-ups and partnerships. This process involves:

  • Collaborating with local healthcare providers, hospitals, and clinics to gather real-time data.
  • Conducting surveys, interviews, and field studies to collect fresh data directly from the source.
  • Continuously refreshing our database to ensure that the information remains current and reliable.
  • Validating secondary data through cross-referencing with primary data to ensure accuracy and relevance.

Combining Secondary and Primary Research

By integrating both secondary and primary research methodologies, we ensure that our database is comprehensive, accurate, and up-to-date. The combined process involves:

  • Merging historical data from secondary research with real-time data from primary research.
  • Conducting thorough data validation and cleansing to remove inconsistencies and errors.
  • Organizing data into a structured format that is easily accessible and usable for various applications.
  • Continuously monitoring and updating the database to reflect the latest developments and trends in the healthcare field.

Through this meticulous process, we create a final database tailored to each region and domain within the healthcare industry. This approach ensures that our clients receive reliable and relevant data, empowering them to make informed decisions and drive innovation in their respective fields.

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Last updated on: 19 June 2024
Updated by: Bhanu Pratap Singh

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