Singapore Alzheimer’s Therapeutics Market Analysis

Singapore Alzheimer’s Therapeutics Market Analysis


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Singapore alzheimer’s therapeutics market valued at $6 Mn in 2022, projected to reach $12 Mn by 2030 with a 9.7% CAGR. The market for medications used to treat Alzheimer's disease is mostly driven by the condition's increasing prevalence, which is fuelled by an aging population. The top pharmaceutical firms in the industry currently operating in the market are Eisai, Biogen, GlaxoSmithKline, Novartis, Pfizer, Roche, Johnson & Johnson, Eli Lilly, AstraZeneca and Merck & Co.

ID: IN10SGPH431 CATEGORY: Pharmaceuticals GEOGRAPHY: Singapore AUTHOR: Dr. Medha Sansanwal

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Singapore Alzheimer’s Therapeutics Market Executive Summary

Singapore alzheimer’s therapeutics market valued at $6 Mn in 2022, projected to reach $12 Mn by 2030 with a 9.7% CAGR.

Alzheimer's disease is a neurological condition that impairs mental health, behavior, and memory. Usually, it starts slowly, gets worse with time, and makes it harder for the person who is affected to perform daily tasks. Nerve cells in Alzheimer's disease die as a result of abnormal brain alterations such as plaque and tangle formation. Alzheimer's disease does not currently have a cure. However, some drugs can help with symptom control and enhance quality of life. These medications treat memory and cognitive issues by changing specific neurotransmitters in the brain. Among these medications are memantine, rivastigmine, and donepezil. Non-pharmacological techniques include keeping a healthy lifestyle, engaging in social and cognitive activities, and fostering a supportive environment, all of which may improve overall illness management.

In Singapore, 5.7% of people 60 years of age and older have dementia, with Alzheimer's disease being the most common kind, affecting about 80,000 people. The population of the country is aging quickly; estimates indicate that by 2030, there will be more than 1 Mn people over the age of 65. This shift in demographics naturally increases the risk of Alzheimer's because the disease is associated with aging. Furthermore, increased public awareness campaigns and better healthcare accessibility lead to more precise diagnoses, which may cause the reported prevalence of Alzheimer's disease to rise as the nation's diagnostic capacities and awareness grow.

The innovative LMTX medication, developed by renowned biotech company TauRx, with its headquarters in Singapore, is about to wrap up Phase II clinical trials. The treatment is specifically intended to target Tau protein aggregation, a major indicator of Alzheimer's disease.

Leading Japanese pharmaceutical company Eisai Co., Ltd. is rapidly collecting real-world data and monitoring post-approval for the ground-breaking Alzheimer's medication Leqembi (lecanemab). Notably, Leqembi is the first and only medication approved to treat Alzheimer's, and thanks to a strategic partnership with Biogen Inc., it is now available in Singapore. By collecting more data, Eisai aims to improve the understanding of Leqembi's long-term effectiveness and safety profile, which will help advance the field of Alzheimer's treatment.

Singapore alzheimer's therapeutics market

Market Dynamics

Market Growth Drivers

Aging Population: Singapore's population is aging quickly; by 2030, there will be more than a Mn people in Singapore who are 65 years of age or older. Alzheimer's prevalence climbs with age, therefore this directly raises the risk of developing the disease. Because of this change in the population, there will be more patients available, which will increase the demand for efficient therapies.

Emerging Treatment Options: Exciting developments in Alzheimer's therapy late-stage clinical studies address different facets of the illness and provide hope for better treatments. The Etermis clinical study for EMERG-01, which focuses on Tau protein aggregation, is an example of how regional efforts can advance global healthcare and ultimately help the market for Alzheimer's medicines grow.

Growing Awareness and Diagnosis: Increased reported prevalence and more precise diagnoses are being produced by public awareness initiatives and better access to medical facilities. This may increase consumer demand for available treatment choices.

Market Restraints

Limited Access to Specialists: Due to the concentration of neurologists and experts treating Alzheimer's disease in urban areas, it might be difficult for rural communities to receive appropriate diagnosis, treatment, and follow-up care. This discrepancy impedes patient results and limits the uptake of Alzheimer's medicines in the market.

High Costs: The high cost of new treatments such as Leqembi places a significant financial burden on patients with Alzheimer's disease and their families. Limited insurance coverage for chronic illnesses exacerbates this issue by forcing many people to choose between costly medical care and other necessities. This can hinder the growth of the market by preventing a significant portion of the population from accessing new medicines.

Lack of Awareness and Stigma: Despite the growing frequency of awareness initiatives, the stigma associated with dementia and Alzheimer's disease in society still prevents people from seeking a diagnosis or the right treatment. This stigma is a notable barrier that keeps the market from reaching a wider segment of the population and serves as a major market constraint.

Healthcare Policies and Regulatory Landscape

The Health Sciences Authority (HSA), a significant organization under the Ministry of Health, oversees Singapore's regulatory environment for therapeutic medications. Ensuring the efficacy, safety, and quality of health products, especially pharmaceuticals, is the responsibility of the HSA, which also manages the approval procedure for new drugs. Before their medications may be promoted and sold in Singapore, pharmaceutical companies must submit thorough applications and go through a rigorous screening process that includes reviewing clinical trial data, safety profiles, and manufacturing standards. Following approval, the HSA conducts post-market surveillance operations, such as adverse event reporting and inspections, to keep an eye on the effectiveness and safety of pharmaceuticals. To ensure that healthcare is affordable for patients, the Ministry of Health (MOH) is also involved in policy, especially when it comes to topics like drug pricing.

Competitive Landscape

Key Players

  • Eisai
  • Biogen
  • GlaxoSmithKline
  • Novartis
  • Pfizer
  • Roche
  • Johnson & Johnson,
  • Eli Lilly
  • AstraZeneca
  • Merck & Co.

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Singapore Alzheimer’s Therapeutics Market Segmentation

By Type

  • Early-Onset Alzheimer's
  • Late-Onset Alzheimer's
  • Familial Alzheimer's disease

By Drug Name

  • Donepezil
  • Rivastigmine
  • Memantine
  • Galantamine
  • Manufactured a combination of memantine and donepezil

By Drug Class

  • Cholinesterase Inhibitors
  • NMDA Receptor Antagonists
  • Manufactured Combination

By End-Users

  • Hospitals
  • Specialty Clinics
  • Homecare
  • Others

By Distribution Channel

  • Hospital pharmacies
  • Drug stores
  • Retail pharmacies
  • Online pharmacies
  • Other distribution channel

Methodology for Database Creation

Our database offers a comprehensive list of healthcare centers, meticulously curated to provide detailed information on a wide range of specialties and services. It includes top-tier hospitals, clinics, and diagnostic facilities across 30 countries and 24 specialties, ensuring users can find the healthcare services they need.​

Additionally, we provide a comprehensive list of Key Opinion Leaders (KOLs) based on your requirements. Our curated list captures various crucial aspects of the KOLs, offering more than just general information. Whether you're looking to boost brand awareness, drive engagement, or launch a new product, our extensive list of KOLs ensures you have the right experts by your side. Covering 30 countries and 36 specialties, our database guarantees access to the best KOLs in the healthcare industry, supporting strategic decisions and enhancing your initiatives.

How Do We Get It?

Our database is created and maintained through a combination of secondary and primary research methodologies.

1. Secondary Research

With many years of experience in the healthcare field, we have our own rich proprietary data from various past projects. This historical data serves as the foundation for our database. Our continuous process of gathering data involves:

  • Analyzing historical proprietary data collected from multiple projects.
  • Regularly updating our existing data sets with new findings and trends.
  • Ensuring data consistency and accuracy through rigorous validation processes.

With extensive experience in the field, we have developed a proprietary GenAI-based technology that is uniquely tailored to our organization. This advanced technology enables us to scan a wide array of relevant information sources across the internet. Our data-gathering process includes:

  • Searching through academic conferences, published research, citations, and social media platforms
  • Collecting and compiling diverse data to build a comprehensive and detailed database
  • Continuously updating our database with new information to ensure its relevance and accuracy

2. Primary Research

To complement and validate our secondary data, we engage in primary research through local tie-ups and partnerships. This process involves:

  • Collaborating with local healthcare providers, hospitals, and clinics to gather real-time data.
  • Conducting surveys, interviews, and field studies to collect fresh data directly from the source.
  • Continuously refreshing our database to ensure that the information remains current and reliable.
  • Validating secondary data through cross-referencing with primary data to ensure accuracy and relevance.

Combining Secondary and Primary Research

By integrating both secondary and primary research methodologies, we ensure that our database is comprehensive, accurate, and up-to-date. The combined process involves:

  • Merging historical data from secondary research with real-time data from primary research.
  • Conducting thorough data validation and cleansing to remove inconsistencies and errors.
  • Organizing data into a structured format that is easily accessible and usable for various applications.
  • Continuously monitoring and updating the database to reflect the latest developments and trends in the healthcare field.

Through this meticulous process, we create a final database tailored to each region and domain within the healthcare industry. This approach ensures that our clients receive reliable and relevant data, empowering them to make informed decisions and drive innovation in their respective fields.

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Last updated on: 09 April 2024
Updated by: Dr. Purav Gandhi

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