Brazil Hepatorenal Syndrome Therapeutics Market Analysis

Brazil Hepatorenal Syndrome Therapeutics Market Analysis


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Brazil Hepatorenal Syndrome Therapeutics (HRS) Market is projected to grow from $xx Mn in 2023 to $xx Mn by 2030, registering a CAGR of xx% during the forecast period of 2023 - 2030. People with cirrhosis or acute liver failure who develop kidney impairment are said to have hepatorenal syndrome (HRS), a serious consequence of advanced liver disease. Renal function improvement and halting further decline are the main objectives of treatment for hepatorenal syndrome. The market for HRS Therapeutics is being driven by an increase in the number of patients with liver illnesses, ongoing medical technology breakthroughs, government efforts, and partnerships and collaborations amongst pharmaceutical companies. Ferring Pharmaceuticals, Hospira, Pfizer, Sandoz, Novartis, Grifols, CSL Behring, Octa pharma, and Baxalta are major international participants in the market for treatments for hepatocellular syndrome.

ID: IN10BRRD033 CATEGORY: Rare Diseases GEOGRAPHY: Brazil AUTHOR: Gaurav Bhongale

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Brazil Hepatorenal Syndrome Therapeutics Market Analysis Summary

Brazil Hepatorenal Syndrome Therapeutics Market is valued at around $29.8 Mn in 2022 and is projected to reach $88.84 Mn by 2030, exhibiting a CAGR of 14.63% during the forecast period 2023-2030.

People with cirrhosis or acute liver failure who develop kidney impairment are said to have hepatorenal syndrome (HRS), a serious consequence of advanced liver disease. Instead of structural kidney disease, it is seen as a functional renal impairment. Although the precise origin of HRS is unknown, it is thought to be predominantly influenced by hemodynamic abnormalities and decreased renal perfusion as a result of changes in systemic and splanchnic circulation. HRS is often divided into Type 1 and Type 2 categories.

The hallmark of type 1 HRS is a rapid and progressive loss in kidney function, frequently accompanied by a brief doubling of blood creatinine (less than two weeks). Without treatment, it has an extremely bad prognosis and a high fatality rate within a few weeks.

A more gradual and sustained loss in kidney function over a longer period of time characterises type 2 HRS. Compared to Type 1 HRS, it has a more varied course and a typically better prognosis.

Clinical criteria and the elimination of any other probable causes of renal dysfunction form the foundation of the diagnosis of HRS. The diagnosis is supported by laboratory tests that measure blood creatinine, urine production, and other indicators of liver and renal function.

The market for HRS Therapeutics is being driven by an increase in the number of patients with liver illnesses, ongoing medical technology breakthroughs, government efforts, and partnerships and collaborations among pharmaceutical companies. Ferring Pharmaceuticals, Hospira, Pfizer, Sandoz, Novartis, Grifols, CSL Behring, Octa Pharma, and Baxalta are major international participants in the market for treatments for hepatocellular syndrome.

Market Dynamics

Market Drivers

Liver disease prevalence: Since HRS is a consequence of advanced liver disease, the need for HRS treatment alternatives is rising as a result of the rising prevalence of liver illness.

Medical Technology Advancements: Ongoing improvements in medical technology, including diagnostic instruments and imaging methods, help to identify HRS earlier and manage it more effectively.

Healthcare Access: Patients with HRS have access to medical specialists and specialised care because healthcare facilities and services are widely available worldwide. The ability to treat HRS patients is further aided by the availability of liver transplant facilities and tertiary care hospitals.

Government Programs and Policies: Government programs, such as Medicare and Medicaid, are crucial in supplying healthcare and paying for HRS-related therapies. The market for HRS medicines is also impacted by regulatory guidelines and clearances from organisations like the Food and Drug Administration (FDA).

Partnerships & Cooperation: Collaborations and collaborations with pharmaceutical firms, academic institutions, and healthcare organisations foster information exchange, clinical trials, and the creation of ground-breaking HRS therapies.

Market Development

The first and only FDA-approved medication, TERLIVAZ, is recommended for the treatment of people with HRS involving a fast decline in kidney function, a serious illness necessitating hospitalisation.

Key players

Novartis Pfizer Sanofi Gilead Sciences AbbVie AstraZeneca Janssen Takeda BMS Celgene

1. Executive Summary
1.1 Disease Overview
1.2 Global Scenario
1.3 Country Overview
1.4 Healthcare Scenario in Country
1.5 Patient Journey
1.6 Health Insurance Coverage in Country
1.7 Active Pharmaceutical Ingredient (API)
1.8 Recent Developments in the Country

2. Market Size and Forecasting
2.1 Epidemiology of Disease
2.2 Market Size (With Excel & Methodology)
2.3 Market Segmentation (Check all Segments in Segmentation Section)

3. Market Dynamics
3.1 Market Drivers
3.2 Market Restraints

4. Competitive Landscape
4.1 Major Market Share

4.2 Key Company Profile (Check all Companies in the Summary Section)

4.2.1 Company
4.2.1.1 Overview
4.2.1.2 Product Applications and Services
4.2.1.3 Recent Developments
4.2.1.4 Partnerships Ecosystem
4.2.1.5 Financials (Based on Availability)

5. Reimbursement Scenario
5.1 Reimbursement Regulation
5.2 Reimbursement Process for Diagnosis
5.3 Reimbursement Process for Treatment

6. Methodology and Scope

Market Segmentations For Brazil Hepatorenal Syndrome Therapeutics Market

By Drugs

  • Terlipressin
  • Noradrenaline
  • Octreotide
  • Albumin
  • Other
  • Others

By Treatment

  • Liver Transplantation
  • Renal replacement therapy
  • Pharmacologic Therapy
  • Others

By Distribution Channel

  • Hospital Pharmacies
  • Retail Pharmacies

By End User

  • Hospitals
  • Specialty Clinics

Insights10 will provide you with the reports within 10 key parameters which are:

  1. Market Overview
  2. Market Growth Drivers & Restraints
  3. Epidemiology of Disease Type
  4. Market Segmentation
  5. Market Share
  6. Competitive Landscape
  7. Key Company Profiles
  8. Healthcare Policies & Regulatory Framework
  9. Reimbursement Scenario
  10. Factors Driving Future Growth

Based on our many years of experience, we believe that these are the parameters that are critical to decision-making for business stakeholders. Our focused approach to developing reports focused on 10 key parameters, enabled us to arrive at the name “Insights10”.

 

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Stage II: Market Data Analysis and Statistical Model

Market Trends: We generally look at macro parameters and micro indicators. The macro parameters include changes in government policies, demand and supply of the market, government intervention programs, and major market share. The micro indicators are GDP growth, market size, market volume, etc. We also understand nuances specific to each country like the US, Canada, India, Germany, etc., and have worked across 60+ countries and hence not only understand global trends but how these differ by country, how payment models, market structure, cultural parameters, etc. differ in each country.

Market Sizing and Analysis: Our expert data analytics team has created various market forecast models by employing the top-down approach i.e. starting with the large overall market and segmenting different areas and the bottom-up approach i.e. starting with population and epidemiology and rolling up based on spend, etc., estimating the size of the market, and distributing among the geographic and/or product segments.

The top-down approach is mainly used for new product forecasting and the bottom-up approach is used for demand estimation of any product for different countries summed up to form the total market. We are able to round off insights and build stronger forecasts because we always do both these methods and triangulate the final numbers.

The study on the market covers the analysis of the leading geographies such as Asia-Pacific, Africa, Europe, Middle East, North America, and  Latin America for the period of 2022 to 2030. The qualitative analysis covers the industry landscape and trends, market opportunities, competitive landscape, and policy and regulatory scenario, and the quantitative analysis covers different market estimates and forecasts.

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We make sure to finalize the numbers in alignment with the market research. Firstly, our internal experts ensure thorough validation and checking to ensure accurate and precise analysis and then validation is also done using a multiple-data analysis model. Two-level validation is done and entails the finalization of the report scope and the way of representation pattern.

 

 

Stage III: Interpretation and Presentation

Analysis & Interpretation: The information gathered is then analyzed and synthesized. The second series of interviews are done if necessary to check and validate. The future opportunities are analyzed by understanding product commercialization and many other factors. It also comprises the analysis of data discrepancies observed across various data sources. Information procured from secondary and primary results is then, interpreted by considering the following parameters: (a partial list)

  • Establishing market drivers and trends
  • Analyzing the regulatory landscape to understand future growth
  • Market Segment based analysis to obtain revenue/volume
  • ​Analyzing current needs and determining penetration to estimate the market

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The foreign exchange rates are calculated on the respective dates and for the respective regions covered in the study.

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Last updated on: 04 July 2023
Updated by: Shivam Zalke

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